Remote ischemic conditioning for stroke: clinical data, challenges, and future directions
نویسندگان
چکیده
منابع مشابه
Remote ischemic per-conditioning: a novel therapy for acute stroke?
BACKGROUND AND PURPOSE Remote ischemic preconditioning is a phenomenon by which a short period of sublethal ischemia to an organ protects against subsequent ischemia in another organ. We have recently demonstrated that remote ischemic conditioning by transient hind limb ischemia delivered during ischemia and before reperfusion can provide potent cardioprotection, a phenomenon we termed per-cond...
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Aetna considers remote ischemic conditioning experimental and investigational for the treatment of aneurysmal subarachnoid hemorrhage, myocardial infarction, primary graft dysfunction following lung transplantation, spinal cord injury, traumatic brain injury, and other indications (e.g., for cardiac, cognitive, pulmonary and renal protection during cardiac surgery, endovascular aneurysm repair,...
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In remote ischemic conditioning (RIC), brief, reversible episodes of ischemia with reperfusion in one vascular bed, tissue, or organ confer a global protective phenotype and render remote tissues and organs resistant to ischemia/reperfusion injury. The peripheral stimulus can be chemical, mechanical, or electrical and involves activation of peripheral sensory nerves. The signal transfer to the ...
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Remote ischemic conditioning (RIC) is the phenomenon whereby brief episodes of peripheral ischemia-reperfusion, typically applied to ≥1 limbs by inflation–deflation of a standard blood pressure cuff, increase the tolerance of the myocardium to a sustained ischemic episode. Compelling preclinical evidence of infarct size reduction with RIC, together with promising results from small, proof-of-co...
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Evaluative conditioning (EC) is generally considered to be one of the routes via which likes and dislikes are acquired. We identify recent trends in EC research and speculate about the topics that will dominate future research on EC. Many of the recent developments in EC research were shaped by functional definitions of EC that refer only to environmental conditions, but not to mental processes...
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ژورنال
عنوان ژورنال: Annals of Clinical and Translational Neurology
سال: 2018
ISSN: 2328-9503
DOI: 10.1002/acn3.691